The School of Medicine is part of the University of Louisville Health Sciences Center, located in the heart of downtown Louisville. Immediately east of the School is the University of Louisville Hospital, the principal teaching hospital of the University, and within two blocks are most affiliated hospitals. The center of activity for preclinical students is the Instructional Building which is a functional and modern three-story structure designed on the unit laboratory concept of teaching the preclinical disciplines. It houses both the first and second year medical classes and provides each student study and laboratory space in the newly renovated unit labs which include 18 small study/group rooms (with computer workstations) on each floor. The lecture halls are designed to utilize the latest teaching concepts and each floor is supplied with small lecture-seminar rooms. A computer classroom containing 33 workstations provides computer-assisted instruction and consultative research services to faculty, staff and students.

Connected to the Instructional Building are the School of Dentistry and a fourteen-floor tower building housing the Medical School's departments of Anatomical Sciences and Neurobiology, Biochemistry, Microbiology and Immunology, Pharmacology and Toxicology, and Physiology and Biophysics and the administrative offices of the Departments of Psychiatry and Behavioral Sciences and Neurology. Also connected is the Commons Building which houses the Kornhauser Health Sciences Library, an auditorium seating 500 and a cafeteria.

THE ALUMNI CENTER FOR MEDICAL EDUCAITON

The Alumni Center for Medical Education, located on the third floor of the Instructional Building, houses two state-of-the-art clinical education sites, the John M. and Dorothy Paris Patient Simulation Center and the Standardized Patient Clinic. Students have opportunities to develop and hone their clinical skills in both of these facilities. The John M. and Dorothy Paris Simulation Lab houses five computer-driven human patient simulators, making it the largest facility of its kind currently housed in a school of medicine. Simulators can mimic the physiology and pathophysiology of a person of any age; students can administer cardiac massage, ventilation, gases, drugs, etc., and observe the body's reaction. Since the basic factors of physiology can be controlled, the simulators can also be used to demonstrate disease sates to recreate realistic abnormal physiology. The Standardized Patient Clinic contains eight fully equipped examination rooms; student performance can be observed from a centrally located control room or videotaped for later review with a faculty member or standardized patient. Standardized patients are trained to present with particular symptoms and provide students with feedback about their history taking, examination, and communication skills; they provide students with realistic, risk free opportunities to interact with patients prior to working with them in clinical settings. Students work with standardized patients beginning in their first year in the program.

THE ACKERLY CHILD PSYCHIATRIC SERVICE

This is an 18 bed inpatient unit now located in Kosair-Children's Hospital. It was opened in 1975 under the Child Psychiatric Services of the Department of Psychiatry and Behavioral Sciences for children up to age 16 in need of a diagnostic evaluation or short-term treatment for emotional problems. All patients are involved in a school program, art and activity therapy, and individual therapy, as well as group, family and medication therapy as needed. Staff from the Bingham Child Guidance Clinic are intimately involved in the inpatient program.

THE BINGHAM CHILD GUIDANCE CLINIC, INC

Located on the second floor of Norton Hospital building at 200 East Chestnut Street, this clinic is under the professional supervision of the Department of Psychiatry and Behavioral Sciences of the School of Medicine and is part of the postgraduate training program in child psychiatry. It is financially sponsored by the United Way and by federal and department funds of the Department of Psychiatry. The clinic is the fourth oldest Child Guidance Clinic in the nation, and is an approved training center for psychiatrists, medical students, psychologists, social workers, nurses, and school teachers.

THE KORNHAUSER HEALTH SCIENCES LIBRARY

The Kornhauser Health Sciences Library, located in the Commons Building, houses materials and services to meet the information requirements of the Schools of Medicine, Dentistry, Nursing, and Allied Health Sciences and the Jefferson County Medical Society. The Library's collections now exceed 200,000 volumes, and more than 1,800 current journal subscriptions. The collections provide a significant resource for all health care practitioners in the Louisville metropolitan area and western Kentucky. Minerva, the University Libraries computer-based catalog, provides quick and easy access to the collections.

Services of the Library include circulation of materials, interlibrary loan, reference assistance and literature searching. A large collection of audiovisual materials supplements the more traditional book and journal collections. Computer assisted instructional programs, electronic resources and Internet/World Wide Web access are available on workstations within the Library. The Library also provides both on-site and remote access to MEDLINE and other research databases.

The Library, which was founded in 1837 as the Library of the Louisville Medical Institute, houses a rare book and manuscript collection which includes a valuable body of historical manuscripts documenting the history of medical training and health care practices in Kentucky during the nineteenth and twentieth centuries. The Library was named in honor of the late Dr. Sidney Isaac Kornhauser, Professor of Anatomy.

Additional information about the Kornhauser Health Sciences Library can be found at www.louisville.edu/library/kornhauser or by calling 852-5771.

THE KENTUCKY LIONS EYE RESEARCH INSTITUTE

This recently extended complex of 64,000 square feet includes the Department of Ophthalmology and Visual Sciences, The Kentucky Lions Eye Research Institute, the Rounsavall Eye Clinic, The Kentucky Lions Eye Bank and The Kentucky Lions Eye Foundation. About two-thirds of the center is dedicated to laboratory research in visual sciences. The center provides the highest standard of patient care in all specialty areas of Ophthalmology. A broad range of basic and clinical research activities are strongly supported by federal and private funding agencies. Educational activities include a residency training program and a unique Ph.D. program in Visual Sciences.

THE MEDICAL-DENTAL RESEARCH BUILDING

This seven-story 120,000 square foot structure is dedicated primarily to scientific investigation. Departments of the School of Medicine currently using the building for research and clinical studies include Anatomical Sciences and Neurobiology, Biochemistry, Medicine, Obstetrics and Gynecology, Pathology and Laboratory Medicine, Pediatrics, Psychiatry and Surgery.

JAMES GRAHAM BROWN CANCER CENTER

The James Graham Brown Cancer Center is an outpatient facility designed for a multidisciplinary approach to the research and treatment of patients with cancer. Located in the building are the Department of Radiation Oncology, the Divisions of Medical Oncology, Surgical Oncology, Dental Oncology/Maxillofacial Prosthodontics, and Gynecologic Oncology. The Henry Vogt Cancer Research Institute is located on the top two floors of the Center. The Center serves as a training site for medical students and residents in oncology-related fields.

THE KELLER CHILD PSYCHIATRY RESEARCH CENTER

This 8,500-square-foot research facility is for the study and treatment of emotional disorders in families and children. The Center houses a Partial Hospitalization Program for children between the ages of 6 and l6. Ten children come 5 days per week for therapeutic and educational treatment. Fellows and Residents in Psychiatry, Psychology, Social Work and Expressive Therapy rotate through this facility for training in their specialty.

THE COMPREHENSIVE HEALTH CARE CENTER FOR HIGH RISK INFANTS AND CHILDREN (CHILDREN AND YOUTH PROJECT)

This center occupies l0,000 square feet of space, on the first floor of "K" Building which is located on the corner of Floyd and Abraham Flexner Way. This unit serves as a model for comprehensive health care for children born to high medical risk mothers and those residing in low socioeconomic areas. There are more than 22,400 clinic visits a year. It is a model for pediatrics, pedodontics, nursing, nutrition, social services, psychology, audiology, and other health specialities. It is a major outpatient teaching facility for the Department of Pediatrics providing learning experience for medical, dental and nursing disciplines.

THE KOSAIR CHARITIES PEDIATRIC CENTER

The Kosair Charities Pediatric Center, 571 South Floyd Street, is housed on the top two floors of the Department of Pediatrics academic and administrative offices and the Weisskopf Child Evaluation Center(CEC)is located on the bottom two floors. The CEC is a tertiary center serving children with developmental disorders. It was established in 1965 to serve children from birth to the age of 16 who may be at risk for or have mental retardation, birth defects and/or genetic disorders, learning disabilities, autism, or Attention Deficit Hyperactivity Disorder. The Center also serves children of average or above average intelligence when there is a concern about attention, hyperactivity, behavior, and school performance. Through its varied programs, the Center provides comprehensive multi-disciplinary evaluations of children and their families, limited evaluations where assessment is focused in one or just a few areas, early identification of infants, and children at risk for developmental disabilities, genetic evaluations and counseling services, as well as complete cytogenetic laboratory services. Specialized treatment programs are available in the areas of speech-language therapy and occupational therapy.

Comprehensive diagnostic and treatment services for children with autism and their families are provided through the Center's WHAS Crusade for Children Autism Project. The Center also supports research in the area of developmental and genetic disabilities, and provides teaching, training, and supervision to pediatric residents, and others at U of L. The professional staff is composed of pediatricians trained as pediatric developmental specialists, child psychologists, education specialists, speech-language pathologists, occupational therapists, physical therapists, social workers, geneticists, genetic associates, and nurses. Operating as a nonprofit facility for the University of Louisville School of Medicine, funding for the Center is provided through various federal, state, and local sources. The Center is now located in its new and permanent home in the Kosair Charities Pediatric Center, 571 South Floyd St., Suite 100.

KIDNEY DISEASE CENTER

The Kidney Disease Center is located on the corner of Chestnut and Preston Streets and houses the Division of Nephrology of the Department of Medicine. The Nephrology clinics, a dialysis unit, provide treatment for patients with renal disease and hypertension, for recipients of kidney transplants and for patients on chronic dialysis.

RESEARCH RESOURCES CENTER

The Research Resources Center (RRC) is the University of Louisville's central, state-of-the-art animal care facility. The facility is designed to support the sophisticated research of University faculty who employ animal models to study the causes, mechanisms, and cures of human disease. The RRC consists of approximately 20,000 square feet of space devoted to the ethical and humane care of laboratory animals and is complemented by 18,000 square feet in the Delia b. Baxter Building. The facility is under the direction of a full-time veterinarian. The University of Louisville and the RRC embrace the standards set forth by the American Association for the Accreditation of Laboratory Animal Care (AAALC), the "Guide for the Care and Use of Laboratory Animals" (Institute of Laboratory Animal Resources, National Research Council, National Academy Press, 1996) and the ethical principles and practices of the veterinary profession. The University of Louisville Animal Care and Use Committee is constituted according to federal law and has the responsibility for monitoring all aspects of animal care and use at the institution. The Committee also provides the University administration and federal agencies with assurances that the program for animal care and use meets the high standards necessary to conduct biomedical research.

DONALD E. BAXTER, M.D. BIOMEDICAL RESEARCH BUILDING

The Baxter Research Building is a 115,000 sq. ft. facility containing 48 research laboratories, a 100 seat research seminar room, and a small transgenic animal facility. Research programs housed in this facility include transplantation immunology (Institute for Cellular Therapeutics), pediatrics (Kosair ChildrenÕs Hospital Research Institute), Oncology, Center for Genetics and Molecular Medicine, Cardiology, and Nephrology.